An indication refers to anything that makes a certain type of treatment advisable. For example, individuals who suffer from symptoms of depression have an indication for treatment with therapy and a possible SSRI. Individuals who suffer from symptoms of anxiety may have an indication for anxiety treatment, such as therapy and a possible benzodiazepine. Indications come in all shapes and forms, and they are usually identified by medical professionals. There are even situations where individuals might have an indication for taking a psychedelic substance. For example, individuals who suffer from treatment-resistant depression could be given psychedelic substances in conjunction with therapy as an alternative treatment option.